Regulation of cytoplasmic dihydrotestosterone binding in dog prostate by 17 beta-estradiol.
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چکیده
منابع مشابه
Regulation of cytoplasmic dihydrotestosterone binding in dog prostate by 17 beta-estradiol.
17 beta-estradiol enchances androgen-induced prostate growth in the castrate dog to a degree comparable to that seen in spontaneous prostatic hypertrophy. To investigate the mechanism of this synergism, cytosol androgen binding was measured by a density gradient technique in prostates of control and 17 beta-estradiol-treated castrate dogs. [3H]Dihydrotestosterone was bound principally to a moie...
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chased from New England Nuclear, Boston, Mass. The pun ity (>94.0%) was checked by thin-layer chromatography. The antiestrogenic compound U. 11,100 (Nafoxidine) was a gift from the Upjohn Company, Kalamazoo, Mich. Cypro terone acetate was provided by Schening AG, Berlin, Gen many. Agar purum, human serum albumin, and rabbit anti serum against human serum albumin were obtained from Behningwerke,...
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ACKNOWLEDGEMENTS Foremost, I would like to sincerely express my gratitude to my mentor Dr. James Simpkins for his continued support, encouragement, sound advice and for his strategic ideas that contributed to the betterment of my thesis work and helped me meet my timelines. This work would not have been possible without him. Also, I would like to sincerely appreciate Dr. Simpkins for his kind a...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1979
ISSN: 0021-9738
DOI: 10.1172/jci109310